Making, Exporting, and Modulating Wnts

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Decision Making in DRM System Rights Exporting

Digital rights management (DRM) has been widely used in copyright protection. The nature of DRM leads to incompatibility between different DRM systems. Many authors have produced solutions for generating DRM interoperability. However, decisions making in rights exporting, identified as one of the most important aspects in DRM interoperability, still requires intensive research effort. This thes...

متن کامل

When Wnts antagonize Wnts

Secreted Wnt ligands appear to activate a variety of signaling pathways. Two papers in this issue now present genetic evidence that "noncanonical" Wnt signaling inhibits the "canonical" Wnt/beta-catenin pathway. Westfall et al. (2003a) show that zebrafish embryos lacking maternal Wnt-5 function are dorsalized due to ectopic activation of beta-catenin, whereas Topol et al. (2003) report that cho...

متن کامل

The Wnts

How do Wnts work? Developmental and cancer biologists have feverishly dissected the mechanism of Wnt signal transduction (see Figure; homologous vertebrate/invertebrate proteins are indicated in the legend). The prevailing dogma is that the Wnt signal causes β-catenin/Armadillo to accumulate in the nucleus where it acts together with the transcription factor TCF/LEF/Pangolin. But this might not...

متن کامل

Regenerating Wnts

Research in recent years challenged what we once thought of as the canonical function of signaling proteins to reveal new and surprising mechanisms of action. Morphogens, like Wnts, BMPs, or SHHs, long thought to be the factors that provide positional information to specify cell fate and proliferation have turned out to be as important for synaptogenesis, axonal growth, and guidance during both...

متن کامل

Wnt signaling in bone development and disease: making stronger bone with Wnts.

The skeleton as an organ is widely distributed throughout the entire vertebrate body. Wnt signaling has emerged to play major roles in almost all aspects of skeletal development and homeostasis. Because abnormal Wnt signaling causes various human skeletal diseases, Wnt signaling has become a focal point of intensive studies in skeletal development and disease. As a result, promising effective t...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Trends in Cell Biology

سال: 2016

ISSN: 0962-8924

DOI: 10.1016/j.tcb.2016.05.011